Thursday, December 9, 2010

Guggul stimulates thyroid hormone production

Guggul is used in several herbal weight loss formulas. One of the reasons is that Guggul has been shown in research studies to significantly stimulate the thyroid by increasing production of thyroid hormones.
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Guggul extract consisting of guggul lipid and guggulsterones was administered to mice for 15 days. There was significantly increased serum triiodothyronine (T3) and significantly decreased hepatic lipid peroxidation. Thyroxine (T4) and triiodothyronine (T3) are the two important hormones produced by the thyroid and their healthy ratio is key to maintaining normal thyroid function. The T3/T4 ratio in normal thyroid function is 15.89, in Hypothyroidism it is 24.12 and in hyperthyroidism it is 19.5.

Thyroid hormones are necessary for the utilization of carbohydrates, protein synthesis and breakdown of lipids. Metabolism is affected by thyroid hormone levels and improved metabolism helps the body to burn fat and utilize calories effectively. The ability of guggul to regulate lipids may be related to its thyroid stimulating functions.

When combined with some thyroid medications, Z-guggulsterone increased the uptake of iodine by the thyroid gland as well as oxygen uptake in the liver and bicep tissues. Gugulipid significantly reduces the bioavailability of the drugs Propranolol and Diltiazem and should not be taken by those who are on these drugs. Guggul may increase the effects of aspirin, nonsteroidal anti-inflammatory drugs, and warfarin.

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Guggul Information and benefits


  1. Thyroid? I'm a hypo, too and I gained too much weight last summer. I am extremely tired and lethargic but after being on thyroid supplements , I am feeling better.

  2. The guggul plant has the same genus as the myrrh mentioned in the Bible. Maybe subclinical hypothyroid people who can't get supplemental thyroid prescribed could try this Ayurvedic remedy from India to see if it helps increase metabolism, lower cholesterol, and help with weight loss and arthritis.